EC number:5.1.3.14
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.3 Acting on carbohydrates and derivatives |
| ID: | 5.1.3.14 |
|---|---|
| Description: | UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing). |
| Alternative Name: |
Uridine diphosphoacetylglucosamine 2'-epimerase. Uridine diphospho-N-acetylglucosamine 2'-epimerase. Uridine diphosphate-N-acetylglucosamine-2'-epimerase. UDP-N-acetyl-D-glucosamine 2-epimerase. UDP-GlcNAc-2-epimerase. |
| Cath: | 3.30.420.40; 3.40.50.20; 3.40.50.200; 3.40.50.2000; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.1.3.14 |
| BRENDA Enzyme Link: | BRENDA 5.1.3.14 |
| KEGG Enzyme Link: | KEGG5.1.3.14 |
| BioCyc Enzyme Link: | BioCyc 5.1.3.14 |
| ExPASy Enzyme Link: | ExPASy5.1.3.14 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.3.14 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.3.14 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.3.14 |
| IntEnz Enzyme Link: | IntEnz 5.1.3.14 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.3.14 |
| RHEA:17213 | UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymatic formation of uridine diphosphate N-acetyl-D-mannosamine. | Kawamura T, Kimura M, Yamamori S, Ito E | 1978 May 25 | 418068 |
| Biosynthesis of enterobacterial common antigen in Escherichia coli. Biochemical characterization of Tn10 insertion mutants defective in enterobacterial common antigen synthesis. | Meier-Dieter U, Starman R, Barr K, Mayer H, Rick PD | 1990 Aug 15 | 2166030 |
| Active site mutants of the "non-hydrolyzing" UDP-N-acetylglucosamine 2-epimerase from Escherichia coli. | Samuel J, Tanner ME | 2004 Jul 1 | 15210128 |
| Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant: gene mnaA (yvyH) encodes the UDP-N-acetylglucosamine 2-epimerase. | Soldo B, Lazarevic V, Pooley HM, Karamata D | 2002 Aug | 12107153 |
| The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases. | Campbell RE, Mosimann SC, Tanner ME, Strynadka NC | 2000 Dec 12 | 11106477 |