EC number:5.1.3.18
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.3 Acting on carbohydrates and derivatives |
| ID: | 5.1.3.18 |
|---|---|
| Description: | GDP-mannose 3,5-epimerase. |
| Cath: | 3.40.50.720; 3.90.25.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.1.3.18 |
| BRENDA Enzyme Link: | BRENDA 5.1.3.18 |
| KEGG Enzyme Link: | KEGG5.1.3.18 |
| BioCyc Enzyme Link: | BioCyc 5.1.3.18 |
| ExPASy Enzyme Link: | ExPASy5.1.3.18 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.3.18 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.3.18 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.3.18 |
| IntEnz Enzyme Link: | IntEnz 5.1.3.18 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.3.18 |
| RHEA:11144 | GDP-alpha-D-mannose = GDP-beta-L-galactose |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| GDP-D-mannose: GDP-L-galactose epimerase from Chlorella pyrenoidosa. | Barber GA, Hebda PA | 1982 | 7098948 |
| The guanosine 5'-diphosphate D-mannose: guanosine 5'-diphosphate L-galactose epimerase of Chlorella pyrenoidosa. Chemical synthesis of guanosine 5'-diphosphate L-galactose and further studies of the enzyme and the reaction it catalyzes. | Hebda PA, Behrman EJ, Barber GA | 1979 May | 443816 |
| Observations on the mechanism of the reversible epimerization of GDP-D-mannose to GDP-L-galactose by an enzyme from Chlorella pyrenoidosa. | Barber GA | 1979 Aug 25 | 224034 |
| Characterization of a GDP-D-mannose 3'',5''-epimerase from rice. | Watanabe K, Suzuki K, Kitamura S | 2006 Feb | 16413588 |
| Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site. | Major LL, Wolucka BA, Naismith JH | 2005 Dec 28 | 16366586 |
| GDP-mannose 3',5'-epimerase forms GDP-L-gulose, a putative intermediate for the de novo biosynthesis of vitamin C in plants. | Wolucka BA, Van Montagu M | 2003 Nov 28 | 12954627 |
| Partial purification and identification of GDP-mannose 3",5"-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway. | Wolucka BA, Persiau G, Van Doorsselaere J, Davey MW, Demol H, Vandekerckhove J, Van Montagu M, Zabeau M, Boerjan W | 2001 Dec 18 | 11752432 |