EC number:5.1.3.19
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.3 Acting on carbohydrates and derivatives |
| ID: | 5.1.3.19 |
|---|---|
| Description: | Chondroitin-glucuronate 5-epimerase. |
| Alternative Name: |
Polyglucuronate 5-epimerase. Dermatan-sulfate 5-epimerase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.1.3.19 |
| BRENDA Enzyme Link: | BRENDA 5.1.3.19 |
| KEGG Enzyme Link: | KEGG5.1.3.19 |
| BioCyc Enzyme Link: | BioCyc 5.1.3.19 |
| ExPASy Enzyme Link: | ExPASy5.1.3.19 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.3.19 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.3.19 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.3.19 |
| IntEnz Enzyme Link: | IntEnz 5.1.3.19 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.3.19 |
| RHEA:21084 | chondroitin 4'-sulfate = dermatan 4'-sulfate |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase. | Malmström A, Aberg L | 1982 Mar 1 | 7092807 |
| Identification of the active site of DS-epimerase 1 and requirement of N-glycosylation for enzyme function. | Pacheco B, Maccarana M, Goodlett DR, Malmström A, Malmström L | 2009 Jan 16 | 19004833 |
| Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2. | Maccarana M, Olander B, Malmström J, Tiedemann K, Aebersold R, Lindahl U, Li JP, Malmström A | 2006 Apr 28 | 16505484 |