| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.3 Acting on carbohydrates and derivatives |
| ID: | 5.1.3.31 |
|---|---|
| Description: | D-tagatose 3-epimerase. |
| Alternative Name: |
L-ribulose 3-epimerase. Ketose 3-epimerase. |
| Cath: | 3.20.20.150; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 5.1.3.31 |
| BRENDA Enzyme Link: | BRENDA 5.1.3.31 |
| KEGG Enzyme Link: | KEGG5.1.3.31 |
| BioCyc Enzyme Link: | BioCyc 5.1.3.31 |
| ExPASy Enzyme Link: | ExPASy5.1.3.31 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.3.31 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.3.31 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.3.31 |
| IntEnz Enzyme Link: | IntEnz 5.1.3.31 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.3.31 |
| RHEA:53268 | L-ribulose = L-xylulose |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C<sub>5</sub> and C<sub>6</sub> Epimerization Reactions. | Shin SM, Cao TP, Choi JM, Kim SB, Lee SJ, Lee SH, Lee DW | 2017 May 15 | 28258150 |
| Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production. | Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K | 2013 | 23470755 |
| RHEA:51544 | D-ribulose = D-xylulose |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production. | Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K | 2013 | 23470755 |
| Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose. | Zhang L, Mu W, Jiang B, Zhang T | 2009 Jun | 19205890 |
| RHEA:43048 | keto-D-tagatose = keto-D-sorbose |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates. | Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S | 2015 Mar 2 | 25655925 |
| Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production. | Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K | 2013 | 23470755 |
| Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose. | Zhang L, Mu W, Jiang B, Zhang T | 2009 Jun | 19205890 |
| Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose. | Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S | 2007 Nov 23 | 17936787 |
| RHEA:42360 | D-psicose = keto-D-fructose |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates. | Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S | 2015 Mar 2 | 25655925 |
| Characterization of a D-psicose-producing enzyme, D-psicose 3-epimerase, from Clostridium sp. | Mu W, Zhang W, Fang D, Zhou L, Jiang B, Zhang T | 2013 Sep | 23660703 |
| Characterization of a novel metal-dependent D-psicose 3-epimerase from Clostridium scindens 35704. | Zhang W, Fang D, Xing Q, Zhou L, Jiang B, Mu W | 2013 | 23646168 |
| A D-psicose 3-epimerase with neutral pH optimum from Clostridium bolteae for D-psicose production: cloning, expression, purification, and characterization. | Jia M, Mu W, Chu F, Zhang X, Jiang B, Zhou LL, Zhang T | 2014 Jan | 23644747 |
| Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production. | Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K | 2013 | 23470755 |
| Overexpression of D-psicose 3-epimerase from Ruminococcus sp. in Escherichia coli and its potential application in D-psicose production. | Zhu Y, Men Y, Bai W, Li X, Zhang L, Sun Y, Ma Y | 2012 Oct | 22760176 |
| Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. | Chan HC, Zhu Y, Hu Y, Ko TP, Huang CH, Ren F, Chen CC, Ma Y, Guo RT, Sun Y | 2012 Feb | 22426981 |
| Cloning, expression, and characterization of a D-psicose 3-epimerase from Clostridium cellulolyticum H10. | Mu W, Chu F, Xing Q, Yu S, Zhou L, Jiang B | 2011 Jul 27 | 21663329 |
| Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose. | Zhang L, Mu W, Jiang B, Zhang T | 2009 Jun | 19205890 |
| Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose. | Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S | 2007 Nov 23 | 17936787 |
| Characterization of an Agrobacterium tumefaciens D-psicose 3-epimerase that converts D-fructose to D-psicose. | Kim HJ, Hyun EK, Kim YS, Lee YJ, Oh DK | 2006 Feb | 16461638 |