Enzyme

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     5. Isomerases
        5.1 Racemases and epimerases
            5.1.3 Acting on carbohydrates and derivatives
ID:5.1.3.31
Description:D-tagatose 3-epimerase.
Alternative Name: L-ribulose 3-epimerase.
Ketose 3-epimerase.
Cath: 3.20.20.150;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.1.3.31
BRENDA Enzyme Link: BRENDA 5.1.3.31
KEGG Enzyme Link: KEGG5.1.3.31
BioCyc Enzyme Link: BioCyc 5.1.3.31
ExPASy Enzyme Link: ExPASy5.1.3.31
EC2PDB Enzyme Link: EC2PDB 5.1.3.31
ExplorEnz Enzyme Link: ExplorEnz 5.1.3.31
PRIAM enzyme-specific profiles Link: PRIAM 5.1.3.31
IntEnz Enzyme Link: IntEnz 5.1.3.31
MEDLINE Enzyme Link: MEDLINE 5.1.3.31
MSA:

5.1.3.31;

Phylogenetic Tree:

5.1.3.31;

Uniprot:
M-CSA:
RHEA:53268 L-ribulose = L-xylulose
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C<sub>5</sub> and C<sub>6</sub> Epimerization Reactions.Shin SM, Cao TP, Choi JM, Kim SB, Lee SJ, Lee SH, Lee DW2017 May 1528258150
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K201323470755

RHEA:51544 D-ribulose = D-xylulose
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K201323470755
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.Zhang L, Mu W, Jiang B, Zhang T2009 Jun19205890

RHEA:43048 keto-D-tagatose = keto-D-sorbose
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates.Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S2015 Mar 225655925
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K201323470755
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.Zhang L, Mu W, Jiang B, Zhang T2009 Jun19205890
Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S2007 Nov 2317936787

RHEA:42360 D-psicose = keto-D-fructose
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates.Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S2015 Mar 225655925
Characterization of a D-psicose-producing enzyme, D-psicose 3-epimerase, from Clostridium sp.Mu W, Zhang W, Fang D, Zhou L, Jiang B, Zhang T2013 Sep23660703
Characterization of a novel metal-dependent D-psicose 3-epimerase from Clostridium scindens 35704.Zhang W, Fang D, Xing Q, Zhou L, Jiang B, Mu W201323646168
A D-psicose 3-epimerase with neutral pH optimum from Clostridium bolteae for D-psicose production: cloning, expression, purification, and characterization.Jia M, Mu W, Chu F, Zhang X, Jiang B, Zhou LL, Zhang T2014 Jan23644747
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K201323470755
Overexpression of D-psicose 3-epimerase from Ruminococcus sp. in Escherichia coli and its potential application in D-psicose production.Zhu Y, Men Y, Bai W, Li X, Zhang L, Sun Y, Ma Y2012 Oct22760176
Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars.Chan HC, Zhu Y, Hu Y, Ko TP, Huang CH, Ren F, Chen CC, Ma Y, Guo RT, Sun Y2012 Feb22426981
Cloning, expression, and characterization of a D-psicose 3-epimerase from Clostridium cellulolyticum H10.Mu W, Chu F, Xing Q, Yu S, Zhou L, Jiang B2011 Jul 2721663329
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.Zhang L, Mu W, Jiang B, Zhang T2009 Jun19205890
Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S2007 Nov 2317936787
Characterization of an Agrobacterium tumefaciens D-psicose 3-epimerase that converts D-fructose to D-psicose.Kim HJ, Hyun EK, Kim YS, Lee YJ, Oh DK2006 Feb16461638