EC number:5.1.3.37
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.3 Acting on carbohydrates and derivatives |
| ID: | 5.1.3.37 |
|---|---|
| Description: | Mannuronan 5-epimerase. |
| Alternative Name: |
Mannuronan C-5-epimerase. C(5)-mannuronan epimerase. Alginate epimerase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.1.3.37 |
| BRENDA Enzyme Link: | BRENDA 5.1.3.37 |
| KEGG Enzyme Link: | KEGG5.1.3.37 |
| BioCyc Enzyme Link: | BioCyc 5.1.3.37 |
| ExPASy Enzyme Link: | ExPASy5.1.3.37 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.3.37 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.3.37 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.3.37 |
| IntEnz Enzyme Link: | IntEnz 5.1.3.37 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.3.37 |
| RHEA:45572 | [(1->4)-beta-D-mannuronosyl](n) = [alginate](n) |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Pseudomonas aeruginosa AlgG is a polymer level alginate C5-mannuronan epimerase. | Franklin MJ, Chitnis CE, Gacesa P, Sonesson A, White DC, Ohman DE | 1994 Apr | 8144447 |
| Catalytic mechanism and mode of action of the periplasmic alginate epimerase AlgG. | Wolfram F, Kitova EN, Robinson H, Walvoort MT, Codée JD, Klassen JS, Howell PL | 2014 Feb 28 | 24398681 |
| Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix. | Douthit SA, Dlakic M, Ohman DE, Franklin MJ | 2005 Jul | 15968068 |
| The dual roles of AlgG in C-5-epimerization and secretion of alginate polymers in Pseudomonas aeruginosa. | Jain S, Franklin MJ, Ertesvåg H, Valla S, Ohman DE | 2003 Feb | 12581364 |
| Characterization of algG encoding C5-epimerase in the alginate biosynthetic gene cluster of Pseudomonas fluorescens. | Morea A, Mathee K, Franklin MJ, Giacomini A, O'Regan M, Ohman DE | 2001 Oct 31 | 11707327 |