Enzyme

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     5. Isomerases
        5.1 Racemases and epimerases
            5.1.99 Acting on other compounds
ID:5.1.99.5
Description:Hydantoin racemase.
Alternative Name: 5'-monosubstituted-hydantoin racemase.
Cath: 3.30.70.360; 3.40.630.10; 3.60.110.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.1.99.5
BRENDA Enzyme Link: BRENDA 5.1.99.5
KEGG Enzyme Link: KEGG5.1.99.5
BioCyc Enzyme Link: BioCyc 5.1.99.5
ExPASy Enzyme Link: ExPASy5.1.99.5
EC2PDB Enzyme Link: EC2PDB 5.1.99.5
ExplorEnz Enzyme Link: ExplorEnz 5.1.99.5
PRIAM enzyme-specific profiles Link: PRIAM 5.1.99.5
IntEnz Enzyme Link: IntEnz 5.1.99.5
MEDLINE Enzyme Link: MEDLINE 5.1.99.5
MSA:

5.1.99.5;

Phylogenetic Tree:

5.1.99.5;

Uniprot:
M-CSA:
RHEA:46624 a D-5-monosubstituted hydantoin = a L-5-monosubstituted hydantoin
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Hydantoinases and related enzymes as biocatalysts for the synthesis of unnatural chiral amino acids.Altenbuchner J, Siemann-Herzberg M, Syldatk C2001 Dec11849938
Site-directed mutagenesis indicates an important role of cysteines 76 and 181 in the catalysis of hydantoin racemase from Sinorhizobium meliloti.Martínez-Rodríguez S, Andújar-Sánchez M, Neira JL, Clemente-Jiménez JM, Jara-Pérez V, Rodríguez-Vico F, Las Heras-Vázquez FJ2006 Dec17132860
Purification and characterization of hydantoin racemase from Microbacterium liquefaciens AJ 3912.Suzuki S, Onishi N, Yokozeki K2005 Mar15784981
Biochemical characterization of a novel hydantoin racemase from Agrobacterium tumefaciens C58.Martínez-Rodríguez S, Las Heras-Vázquez FJ, Clemente-Jiménez JM, Rodríguez-Vico F2004 Feb15016445
Molecular cloning, purification, and biochemical characterization of hydantoin racemase from the legume symbiont Sinorhizobium meliloti CECT 4114.Martínez-Rodríguez S, Las Heras-Vázquez FJ, Mingorance-Cazorla L, Clemente-Jiménez JM, Rodríguez-Vico F2004 Jan14711700
Purification and characterization of the hydantoin racemase of Pseudomonas sp. strain NS671 expressed in Escherichia coli.Watabe K, Ishikawa T, Mukohara Y, Nakamura H1992 Dec1459947
Hydantoin racemase from Arthrobacter aurescens DSM 3747: heterologous expression, purification and characterization.Wiese A, Pietzsch M, Syldatk C, Mattes R, Altenbuchner J2000 Jul 1410949312