EC number:5.2.1.2
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.2 cis-trans-Isomerases |
| 5.2.1 cis-trans Isomerases (only sub-subclass identified to date) |
| ID: | 5.2.1.2 |
|---|---|
| Description: | Maleylacetoacetate isomerase. |
| Alternative Name: |
Maleylacetone isomerase. |
| Cath: | 1.20.1050.10; 3.40.30.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.2.1.2 |
| BRENDA Enzyme Link: | BRENDA 5.2.1.2 |
| KEGG Enzyme Link: | KEGG5.2.1.2 |
| BioCyc Enzyme Link: | BioCyc 5.2.1.2 |
| ExPASy Enzyme Link: | ExPASy5.2.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 5.2.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.2.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.2.1.2 |
| IntEnz Enzyme Link: | IntEnz 5.2.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 5.2.1.2 |
| RHEA:14817 | 4-maleylacetoacetate = 4-fumarylacetoacetate |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. | Tong Z, Board PG, Anders MW | 1998 Apr 15 | 9531472 |
| A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster. | Saisawang C, Wongsantichon J, Ketterman AJ | 2012 Feb 15 | 22082028 |
| Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity. | Polekhina G, Board PG, Blackburn AC, Parker MW | 2001 Feb 13 | 11327815 |
| Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis. | Blackburn AC, Tzeng HF, Anders MW, Board PG | 2000 Feb | 10739172 |