EC number:5.3.1.1

Enzyme

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     5. Isomerases
        5.3 Intramolecular oxidoreductases
            5.3.1 Interconverting aldoses and ketoses, and related compounds
ID:5.3.1.1
Description:Triose-phosphate isomerase.
Alternative Name: Triosephosphate mutase.
Triosephosphate isomerase.
Triose phosphoisomerase.
Phosphotriose isomerase.
Prosite: PDOC00155;
PDB:
PDBScop
1MO0 8031317; 8043695; 8031317; 8043695;
2Y63 8031047; 8043425;
2Y62 8031047; 8043425;
2Y61 8031047; 8043425;
2VXN 8031047; 8043425;
 » show all
Cath: 3.20.20.70; 3.40.50.1260;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.3.1.1
BRENDA Enzyme Link: BRENDA 5.3.1.1
KEGG Enzyme Link: KEGG5.3.1.1
BioCyc Enzyme Link: BioCyc 5.3.1.1
ExPASy Enzyme Link: ExPASy5.3.1.1
EC2PDB Enzyme Link: EC2PDB 5.3.1.1
ExplorEnz Enzyme Link: ExplorEnz 5.3.1.1
PRIAM enzyme-specific profiles Link: PRIAM 5.3.1.1
IntEnz Enzyme Link: IntEnz 5.3.1.1
MEDLINE Enzyme Link: MEDLINE 5.3.1.1

EC number:5.3.1.1

MSA:

5.3.1.1;
Phylogenetic Tree:

5.3.1.1;
Uniprot:
M-CSA:
RHEA:18585 D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4]=[O;H0;+0:5]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Triosephosphate isomerase: a highly evolved biocatalyst.Wierenga RK, Kapetaniou EG, Venkatesan R2010 Dec20694739
Novel listerial glycerol dehydrogenase- and phosphoenolpyruvate-dependent dihydroxyacetone kinase system connected to the pentose phosphate pathway.Monniot C, Zébré AC, Aké FM, Deutscher J, Milohanic E2012 Sep22773791
Triose-phosphate isomerase (TIM) of the psychrophilic bacterium Vibrio marinus. Kinetic and structural properties.Alvarez M, Zeelen JP, Mainfroid V, Rentier-Delrue F, Martial JA, Wyns L, Wierenga RK, Maes D1998 Jan 239442062
Nucleotide sequence of the triose phosphate isomerase gene of Escherichia coli.Pichersky E, Gottlieb LD, Hess JF19846092857
Structural and functional characterization of Mycobacterium tuberculosis triosephosphate isomerase.Connor SE, Capodagli GC, Deaton MK, Pegan SD2011 Dec22120738
Kinetic and structural properties of triosephosphate isomerase from Helicobacter pylori.Chu CH, Lai YJ, Huang H, Sun YJ2008 Apr17957775
Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii.Gayathri P, Banerjee M, Vijayalakshmi A, Azeez S, Balaram H, Balaram P, Murthy MR2007 Feb17242514
Biochemical and functional characterization of triosephosphate isomerase from Mycobacterium tuberculosis H37Rv.Mathur D, Malik G, Garg LC2006 Oct16978361