EC number:5.3.1.16
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.3 Intramolecular oxidoreductases |
| 5.3.1 Interconverting aldoses and ketoses, and related compounds |
| ID: | 5.3.1.16 |
|---|---|
| Description: | isomerase. |
| Alternative Name: |
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. imidazolecarboxamide isomerase. N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4- |
| Cath: | 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.3.1.16 |
| BRENDA Enzyme Link: | BRENDA 5.3.1.16 |
| KEGG Enzyme Link: | KEGG5.3.1.16 |
| BioCyc Enzyme Link: | BioCyc 5.3.1.16 |
| ExPASy Enzyme Link: | ExPASy5.3.1.16 |
| EC2PDB Enzyme Link: | EC2PDB 5.3.1.16 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.3.1.16 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.3.1.16 |
| IntEnz Enzyme Link: | IntEnz 5.3.1.16 |
| MEDLINE Enzyme Link: | MEDLINE 5.3.1.16 |
| RHEA:15469 | 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]=[CH;+0:3]-[NH;+0:4]-[CH;+0:5]1-[O;H0;+0:6]-[*:7]-[*:8]-[CH;+0:9]-1-[OH;+0:10]>>[*:1]-[NH;+0:2]-[CH;+0:3]=[N;H0;+0:4]-[CH2;+0:5]-[C;H0;+0:9](=[O;H0;+0:10])-[*:8]-[*:7]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of the yeast His6 enzyme suggests a reaction mechanism. | Quevillon-Cheruel S, Leulliot N, Graille M, Blondeau K, Janin J, van Tilbeurgh H | 2006 Jun | 16731983 |
| Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates. | Henn-Sax M, Thoma R, Schmidt S, Hennig M, Kirschner K, Sterner R | 2002 Oct 8 | 12356303 |