EC number:5.3.1.21
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.3 Intramolecular oxidoreductases |
| 5.3.1 Interconverting aldoses and ketoses, and related compounds |
| ID: | 5.3.1.21 |
|---|---|
| Description: | Corticosteroid side-chain-isomerase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 5.3.1.21 |
| BRENDA Enzyme Link: | BRENDA 5.3.1.21 |
| KEGG Enzyme Link: | KEGG5.3.1.21 |
| BioCyc Enzyme Link: | BioCyc 5.3.1.21 |
| ExPASy Enzyme Link: | ExPASy5.3.1.21 |
| EC2PDB Enzyme Link: | EC2PDB 5.3.1.21 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.3.1.21 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.3.1.21 |
| IntEnz Enzyme Link: | IntEnz 5.3.1.21 |
| MEDLINE Enzyme Link: | MEDLINE 5.3.1.21 |
| RHEA:17861 | 21-hydroxyprogesterone = 20-hydroxy-3-oxopregn-4-en-21-al |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[OH;+0:5]>>[*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4]=[O;H0;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Studies on 21-3H-labeled corticosteroids: evidence for isomerization of the ketol side chain of 11-deoxycorticosterone by a hamster liver enzyme. | Martin KO, Oh SW, Lee HJ, Monder C | 1977 Aug 23 | 901753 |
| Presence of epimerase activity in hamster liver corticosteroid side chain isomerase. | Monder C, Martin KO, Bogumil J | 1980 Aug 10 | 7391077 |