EC number:5.3.1.23

Enzyme

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     5. Isomerases
        5.3 Intramolecular oxidoreductases
            5.3.1 Interconverting aldoses and ketoses, and related compounds
ID:5.3.1.23
Description:S-methyl-5-thioribose-1-phosphate isomerase.
Alternative Name: S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase.
S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase.
S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase.
MTR-1-P isomerase.
Methylthioribose 1-phosphate isomerase.
5-methylthioribose-1-phosphate isomerase.
5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase.
1-PMTR isomerase.
1-phospho-5'-S-methylthioribose isomerase.
Cath: 1.20.120.1840; 1.20.120.420; 3.40.50.10470;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.3.1.23
BRENDA Enzyme Link: BRENDA 5.3.1.23
KEGG Enzyme Link: KEGG5.3.1.23
BioCyc Enzyme Link: BioCyc 5.3.1.23
ExPASy Enzyme Link: ExPASy5.3.1.23
EC2PDB Enzyme Link: EC2PDB 5.3.1.23
ExplorEnz Enzyme Link: ExplorEnz 5.3.1.23
PRIAM enzyme-specific profiles Link: PRIAM 5.3.1.23
IntEnz Enzyme Link: IntEnz 5.3.1.23
MEDLINE Enzyme Link: MEDLINE 5.3.1.23

EC number:5.3.1.23

MSA:

5.3.1.23;
Phylogenetic Tree:

5.3.1.23;
Uniprot:
M-CSA:
RHEA:19989 5-methylsulfanyl-alpha-D-ribose 1-phosphate = 5-methylsulfanyl-D-ribulose 1-phosphate
RULE(radius=1) [*:1]-[CH;+0:2]1-[O;H0;+0:3]-[*:4]-[*:5]-[CH;+0:6]-1-[OH;+0:7]>>[*:1]-[CH2;+0:2]-[C;H0;+0:6](=[O;H0;+0:7])-[*:5]-[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Intermediates in the conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae.Furfine ES, Abeles RH1988 Jul 152838472
Methionine synthesis from 5'-S-Methylthioadenosine. Resolution of enzyme activities and identification of 1-phospho-5-S methylthioribulose.Trackman PC, Abeles RH1983 Jun 106853500
Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma.Ghoda LY, Savarese TM, Dexter DL, Parks RE Jr, Trackman PC, Abeles RH1984 Jun 106725268