EC number:5.3.1.28
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.3 Intramolecular oxidoreductases |
| 5.3.1 Interconverting aldoses and ketoses, and related compounds |
| ID: | 5.3.1.28 |
|---|---|
| Description: | D-sedoheptulose 7-phosphate isomerase. |
| Alternative Name: |
Sedoheptulose-7-phosphate isomerase. Phosphoheptose isomerase. |
| Cath: | 3.40.50.10490; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.3.1.28 |
| BRENDA Enzyme Link: | BRENDA 5.3.1.28 |
| KEGG Enzyme Link: | KEGG5.3.1.28 |
| BioCyc Enzyme Link: | BioCyc 5.3.1.28 |
| ExPASy Enzyme Link: | ExPASy5.3.1.28 |
| EC2PDB Enzyme Link: | EC2PDB 5.3.1.28 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.3.1.28 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.3.1.28 |
| IntEnz Enzyme Link: | IntEnz 5.3.1.28 |
| MEDLINE Enzyme Link: | MEDLINE 5.3.1.28 |
| RHEA:27489 | 2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[O;H0;+0:3]-[*:4])-[CH;+0:5](-[*:6])-[OH;+0:7]>>([*:1]-[CH2;+0:2]-[C;H0;+0:5](-[*:6])=[O;H0;+0:7].[*:4]-[OH;+0:3]) |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site. | Harmer NJ | 2010 Jul 16 | 20447408 |
| A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei. | Kim MS, Shin DH | 2009 Nov 1 | 19923728 |
| Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. | Taylor PL, Blakely KM, de Leon GP, Walker JR, McArthur F, Evdokimova E, Zhang K, Valvano MA, Wright GD, Junop MS | 2008 Feb 1 | 18056714 |