Enzyme

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     5. Isomerases
        5.3 Intramolecular oxidoreductases
            5.3.2 Interconverting keto- and enol-groups
ID:5.3.2.1
Description:Phenylpyruvate tautomerase.
Alternative Name: Phenylpyruvic keto--enol isomerase.
Phenylpyruvate keto--enol tautomerase.
Cath: 3.30.429.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.3.2.1
BRENDA Enzyme Link: BRENDA 5.3.2.1
KEGG Enzyme Link: KEGG5.3.2.1
BioCyc Enzyme Link: BioCyc 5.3.2.1
ExPASy Enzyme Link: ExPASy5.3.2.1
EC2PDB Enzyme Link: EC2PDB 5.3.2.1
ExplorEnz Enzyme Link: ExplorEnz 5.3.2.1
PRIAM enzyme-specific profiles Link: PRIAM 5.3.2.1
IntEnz Enzyme Link: IntEnz 5.3.2.1
MEDLINE Enzyme Link: MEDLINE 5.3.2.1
MSA:

5.3.2.1;

Phylogenetic Tree:

5.3.2.1;

Uniprot:
M-CSA:
RHEA:17097 3-phenylpyruvate = enol-phenylpyruvate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[*:5]>>[*:1]-[C;H0;+0:2](-[OH;+0:3])=[CH;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation.Fingerle-Rowson G, Kaleswarapu DR, Schlander C, Kabgani N, Brocks T, Reinart N, Busch R, Schütz A, Lue H, Du X, Liu A, Xiong H, Chen Y, Nemajerova A, Hallek M, Bernhagen J, Leng L, Bucala R2009 Apr19188446
Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis.Tan TH, Edgerton SA, Kumari R, McAlister MS, Roe SM, Nagl S, Pearl LH, Selkirk ME, Bianco AE, Totty NF, Engwerda C, Gray CA, Meyer DJ2001 Jul 1511439086