Enzyme

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     5. Isomerases
        5.3 Intramolecular oxidoreductases
            5.3.3 Transposing C=C bonds
ID:5.3.3.13
Description:Polyenoic fatty acid isomerase.
Alternative Name: PFI.
trans-Delta(7,9)-cis-Delta(14,17) isomerase.
Eicosapentaenoate cis-Delta(5,8,11,14,17)-eicosapentaenoate cis-Delta(5)-

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.3.3.13
BRENDA Enzyme Link: BRENDA 5.3.3.13
KEGG Enzyme Link: KEGG5.3.3.13
BioCyc Enzyme Link: BioCyc 5.3.3.13
ExPASy Enzyme Link: ExPASy5.3.3.13
EC2PDB Enzyme Link: EC2PDB 5.3.3.13
ExplorEnz Enzyme Link: ExplorEnz 5.3.3.13
PRIAM enzyme-specific profiles Link: PRIAM 5.3.3.13
IntEnz Enzyme Link: IntEnz 5.3.3.13
MEDLINE Enzyme Link: MEDLINE 5.3.3.13
MSA:

5.3.3.13;

Phylogenetic Tree:

5.3.3.13;

Uniprot:
M-CSA:
RHEA:14889 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate
RULE(radius=1) [*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[CH;+0:5]=[CH;+0:6]-[CH2;+0:7]-[*:8]>>[*:1]-[CH2;+0:2]-[CH2;+0:3]-[CH;+0:4]=[CH;+0:5]-[CH;+0:6]=[CH;+0:7]-[*:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of the substrate binding site of polyenoic fatty acid isomerase, a novel enzyme from the marine alga Ptilota filicina.Wise ML, Rossi J, Gerwick WH1997 Mar 119062129
Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid.Wise ML, Soderstrom K, Murray TF, Gerwick WH1996 Jan 168575565
Biosynthesis of conjugated triene-containing fatty acids by a novel isomerase from the red marine alga Ptilota filicina.Wise ML, Hamberg M, Gerwick WH1994 Dec 277803384
Polyenoic fatty acid isomerase from the marine alga Ptilota filicina: protein characterization and functional expression of the cloned cDNA.Zheng W, Wise ML, Wyrick A, Metz JG, Yuan L, Gerwick WH2002 May 112054482