EC number:5.4.2.12
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.2 Phosphotransferases (phosphomutases) |
| ID: | 5.4.2.12 | ||
|---|---|---|---|
| Description: | Phosphoglycerate mutase (2,3-diphosphoglycerate-independent). | ||
| Alternative Name: |
Phosphoglyceromutase. Phosphoglycerate phosphomutase. Cofactor independent phosphoglycerate mutase. 2,3-diphosphoglycerate-independent phosphoglycerate mutase. | ||
| Prosite: | PDOC00158; | ||
| PDB: |
|
||
| Cath: | 3.30.70.2130; 3.40.720.10; 3.40.1450.10; 3.40.50.1240; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.2.12 |
| BRENDA Enzyme Link: | BRENDA 5.4.2.12 |
| KEGG Enzyme Link: | KEGG5.4.2.12 |
| BioCyc Enzyme Link: | BioCyc 5.4.2.12 |
| ExPASy Enzyme Link: | ExPASy5.4.2.12 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.2.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.2.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.2.12 |
| IntEnz Enzyme Link: | IntEnz 5.4.2.12 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.2.12 |
| RHEA:15901 | 2-phospho-D-glycerate = 3-phospho-D-glycerate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6]-[*:7]-[OH;+0:8]>>[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:8]-[*:7]-[*:6]-[OH;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis. | Mendes V, Maranha A, Alarico S, da Costa MS, Empadinhas N | 2011 | 22355692 |
| Unliganded structure of human bisphosphoglycerate mutase reveals side-chain movements induced by ligand binding. | Patterson A, Price NC, Nairn J | 2010 Nov 1 | 21045285 |
| Development of a mutagenesis, expression and purification system for yeast phosphoglycerate mutase. Investigation of the role of active-site His181. | White MF, Fothergill-Gilmore LA | 1992 Jul 15 | 1386023 |
| The two analogous phosphoglycerate mutases of Escherichia coli. | Fraser HI, Kvaratskhelia M, White MF | 1999 Jul 23 | 10437801 |