EC number:5.4.3.8
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.3 Transferring amino groups |
| ID: | 5.4.3.8 | ||
|---|---|---|---|
| Description: | Glutamate-1-semialdehyde 2,1-aminomutase. | ||
| Alternative Name: |
Glutamate-1-semialdehyde aminotransferase. | ||
| Prosite: | PDOC00519; | ||
| PDB: |
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| Cath: | 3.40.640.10; 3.90.1150.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.3.8 |
| BRENDA Enzyme Link: | BRENDA 5.4.3.8 |
| KEGG Enzyme Link: | KEGG5.4.3.8 |
| BioCyc Enzyme Link: | BioCyc 5.4.3.8 |
| ExPASy Enzyme Link: | ExPASy5.4.3.8 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.3.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.3.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.3.8 |
| IntEnz Enzyme Link: | IntEnz 5.4.3.8 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.3.8 |
| RHEA:14265 | (S)-4-amino-5-oxopentanoate = 5-aminolevulinate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[NH2;+0:3])-[CH;+0:4]=[O;H0;+0:5]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:5])-[CH2;+0:4]-[NH2;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity. | Hennig M, Grimm B, Contestabile R, John RA, Jansonius JN | 1997 May 13 | 9144156 |
| Glutamate-1-semialdehyde aminotransferase from Sulfolobus solfataricus. | Palmieri G, Di Palo M, Scaloni A, Orru S, Marino G, Sannia G | 1996 Dec 1 | 8973563 |
| Characterization of the different spectral forms of glutamate 1-semialdehyde aminotransferase by mass spectrometry. | Brody S, Andersen JS, Kannangara CG, Meldgaard M, Roepstorff P, von Wettstein D | 1995 Dec 12 | 8519748 |
| Mechanism of glutamate semialdehyde aminotransferase. Roles of diamino- and dioxo-intermediates in the synthesis of aminolevulinate. | Pugh CE, Harwood JL, John RA | 1992 Jan 25 | 1730703 |
| Glutamate 1-semialdehyde aminotransferase: anomalous enantiomeric reaction and enzyme mechanism. | Smith MA, Kannangara CG, Grimm B | 1992 Nov 17 | 1445864 |