EC number:5.4.99.12
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.99 Transferring other groups |
| ID: | 5.4.99.12 |
|---|---|
| Description: | tRNA pseudouridine(38-40) synthase. |
| Alternative Name: |
tRNA pseudouridylate synthase I. PSUI. |
| Cath: | 3.30.70.580; 3.30.70.660; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.99.12 |
| BRENDA Enzyme Link: | BRENDA 5.4.99.12 |
| KEGG Enzyme Link: | KEGG5.4.99.12 |
| BioCyc Enzyme Link: | BioCyc 5.4.99.12 |
| ExPASy Enzyme Link: | ExPASy5.4.99.12 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.99.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.99.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.99.12 |
| IntEnz Enzyme Link: | IntEnz 5.4.99.12 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.99.12 |
EC number:5.4.99.12
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:22376 | tRNA uridine(38-40) = tRNA pseudouridine(38-40) |
| RULE(radius=1) | [*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:1]:[c;H0;+0:2](:[*:3]:[nH;+0:4]:[*:5])-[CH;+0:6](-[*:7])-[*:8] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA. | Hur S, Stroud RM | 2007 Apr 27 | 17466622 |
| The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I. | Foster PG, Huang L, Santi DV, Stroud RM | 2000 Jan | 10625422 |