EC number:5.4.99.21
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.99 Transferring other groups |
| ID: | 5.4.99.21 |
|---|---|
| Description: | 23S rRNA pseudouridine(2604) synthase. |
| Cath: | 3.30.2350.10; 3.30.70.1560; 3.30.70.580; 3.10.290.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.99.21 |
| BRENDA Enzyme Link: | BRENDA 5.4.99.21 |
| KEGG Enzyme Link: | KEGG5.4.99.21 |
| BioCyc Enzyme Link: | BioCyc 5.4.99.21 |
| ExPASy Enzyme Link: | ExPASy5.4.99.21 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.99.21 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.99.21 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.99.21 |
| IntEnz Enzyme Link: | IntEnz 5.4.99.21 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.99.21 |
EC number:5.4.99.21
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:38875 | 23S rRNA uridine(2604) = 23S rRNA pseudouridine(2604) |
| RULE(radius=1) | [*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:1]:[c;H0;+0:2](:[*:3]:[nH;+0:4]:[*:5])-[CH;+0:6](-[*:7])-[*:8] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome. | Alian A, DeGiovanni A, Griner SL, Finer-Moore JS, Stroud RM | 2009 May 15 | 19298824 |
| Domain organization and crystal structure of the catalytic domain of E.coli RluF, a pseudouridine synthase that acts on 23S rRNA. | Sunita S, Zhenxing H, Swaathi J, Cygler M, Matte A, Sivaraman J | 2006 Jun 16 | 16712869 |
| Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. | Del Campo M, Kaya Y, Ofengand J | 2001 Nov | 11720289 |