Enzyme

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     5. Isomerases
        5.4 Intramolecular transferases
            5.4.99 Transferring other groups
ID:5.4.99.23
Description:23S rRNA pseudouridine(1911/1915/1917) synthase.
Cath: 1.10.287.150; 1.10.287.1500; 3.30.2350.10; 3.10.290.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.4.99.23
BRENDA Enzyme Link: BRENDA 5.4.99.23
KEGG Enzyme Link: KEGG5.4.99.23
BioCyc Enzyme Link: BioCyc 5.4.99.23
ExPASy Enzyme Link: ExPASy5.4.99.23
EC2PDB Enzyme Link: EC2PDB 5.4.99.23
ExplorEnz Enzyme Link: ExplorEnz 5.4.99.23
PRIAM enzyme-specific profiles Link: PRIAM 5.4.99.23
IntEnz Enzyme Link: IntEnz 5.4.99.23
MEDLINE Enzyme Link: MEDLINE 5.4.99.23
MSA:

5.4.99.23;

Phylogenetic Tree:

5.4.99.23;

Uniprot:
M-CSA:
RHEA:42524 uridine(1911/1915/1917) in 23S rRNA = pseudouridine(1911/1915/1917) in 23S rRNA
RULE(radius=1) [*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:1]:[c;H0;+0:2](:[*:3]:[nH;+0:4]:[*:5])-[CH;+0:6](-[*:7])-[*:8]
Reaction
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References

TitleAuthorsDatePubMed ID
Substrate specificity of the pseudouridine synthase RluD in Escherichia coli.Leppik M, Peil L, Kipper K, Liiv A, Remme J2007 Nov17937767
Crystal structure of the RluD pseudouridine synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli.Sivaraman J, Iannuzzi P, Cygler M, Matte A2004 Jan 214659742