EC number:5.4.99.27
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.99 Transferring other groups |
| ID: | 5.4.99.27 |
|---|---|
| Description: | tRNA pseudouridine(13) synthase. |
| Alternative Name: |
tRNA Psi(13) synthase. |
| Cath: | 1.10.1510.30; 3.30.2340.10; 3.30.2350.20; 3.30.70.3160; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.99.27 |
| BRENDA Enzyme Link: | BRENDA 5.4.99.27 |
| KEGG Enzyme Link: | KEGG5.4.99.27 |
| BioCyc Enzyme Link: | BioCyc 5.4.99.27 |
| ExPASy Enzyme Link: | ExPASy5.4.99.27 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.99.27 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.99.27 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.99.27 |
| IntEnz Enzyme Link: | IntEnz 5.4.99.27 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.99.27 |
EC number:5.4.99.27
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42540 | uridine(13) in tRNA = pseudouridine(13) in tRNA |
| RULE(radius=1) | [*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:1]:[c;H0;+0:2](:[*:3]:[nH;+0:4]:[*:5])-[CH;+0:6](-[*:7])-[*:8] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymatic characterization and mutational studies of TruD--the fifth family of pseudouridine synthases. | Chan CM, Huang RH | 2009 Sep | 19664587 |
| RNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA:{Psi}-synthase Pus7p. | Urban A, Behm-Ansmant I, Branlant C, Motorin Y | 2009 Feb 27 | 19114708 |
| X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold. | Ericsson UB, Nordlund P, Hallberg BM | 2004 May 7 | 15135053 |
| The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. | Behm-Ansmant I, Urban A, Ma X, Yu YT, Motorin Y, Branlant C | 2003 Nov | 14561887 |
| A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya. | Kaya Y, Ofengand J | 2003 Jun | 12756329 |