EC number:5.4.99.29

Enzyme

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     5. Isomerases
        5.4 Intramolecular transferases
            5.4.99 Transferring other groups
ID:5.4.99.29
Description:23S rRNA pseudouridine(746) synthase.
Alternative Name: 23S RNA Psi(746) synthase.
Cath: 3.30.2350.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.4.99.29
BRENDA Enzyme Link: BRENDA 5.4.99.29
KEGG Enzyme Link: KEGG5.4.99.29
BioCyc Enzyme Link: BioCyc 5.4.99.29
ExPASy Enzyme Link: ExPASy5.4.99.29
EC2PDB Enzyme Link: EC2PDB 5.4.99.29
ExplorEnz Enzyme Link: ExplorEnz 5.4.99.29
PRIAM enzyme-specific profiles Link: PRIAM 5.4.99.29
IntEnz Enzyme Link: IntEnz 5.4.99.29
MEDLINE Enzyme Link: MEDLINE 5.4.99.29

EC number:5.4.99.29

MSA:

5.4.99.29;
Phylogenetic Tree:

5.4.99.29;
Uniprot:
M-CSA:
RHEA:42548 23S rRNA uridine(746) = 23S rRNA pseudouridine(746)
RULE(radius=1) [*:1]:[cH;+0:2]:[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:1]:[c;H0;+0:2](:[*:3]:[nH;+0:4]:[*:5])-[CH;+0:6](-[*:7])-[*:8]
Reaction
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References

TitleAuthorsDatePubMed ID
A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).Wrzesinski J, Nurse K, Bakin A, Lane BG, Ofengand J1995 Jun7493321
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.Hoang C, Chen J, Vizthum CA, Kandel JM, Hamilton CS, Mueller EG, Ferré-D'Amaré AR2006 Nov 1717188032
Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.Raychaudhuri S, Niu L, Conrad J, Lane BG, Ofengand J1999 Jul 210383384