EC number:5.4.99.49

Enzyme

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     5. Isomerases
        5.4 Intramolecular transferases
            5.4.99 Transferring other groups
ID:5.4.99.49
Description:Glutinol synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.4.99.49
BRENDA Enzyme Link: BRENDA 5.4.99.49
KEGG Enzyme Link: KEGG5.4.99.49
BioCyc Enzyme Link: BioCyc 5.4.99.49
ExPASy Enzyme Link: ExPASy5.4.99.49
EC2PDB Enzyme Link: EC2PDB 5.4.99.49
ExplorEnz Enzyme Link: ExplorEnz 5.4.99.49
PRIAM enzyme-specific profiles Link: PRIAM 5.4.99.49
IntEnz Enzyme Link: IntEnz 5.4.99.49
MEDLINE Enzyme Link: MEDLINE 5.4.99.49

EC number:5.4.99.49

MSA:

5.4.99.49;
Phylogenetic Tree:

5.4.99.49;
Uniprot:
M-CSA:
RHEA:31859 (S)-2,3-epoxysqualene = glutinol
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[CH3;+0:7])-[CH3;+0:8])=[CH;+0:9]-[*:10]-[CH2;+0:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[*:16]-[CH;+0:17]=[C;H0;+0:18](-[*:19])-[*:20]-[*:21]-[CH;+0:22]=[C;H0;+0:23](-[*:24])-[CH3;+0:25].[*:26]-[C;H0;+0:27]1(-[*:28])-[*:29]-[O;H0;+0:30]-1)>>[*:1]-[C;H0;+0:2]12-[CH2;+0:9]-[*:10]-[C;H0;+0:11]3(-[CH3;+0:6])-[CH2;+0:12]-[CH2;+0:14]-[C;H0;+0:15](-[CH3;+0:7])(-[CH3;+0:8])-[*:16]-[CH;+0:17]-3-[C;H0;+0:18]-1(-[*:19])-[*:20]-[*:21]-[C;H0;+0:22]1(-[CH3;+0:13])-[CH;+0:3]-2-[*:4]-[CH;+0:5]=[C;H0;+0:25](-[C;H0;+0:27](-[*:26])(-[*:28])-[*:29]-[OH;+0:30])-[CH;+0:23]-1-[*:24]
Reaction
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References

TitleAuthorsDatePubMed ID
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.Wang Z, Yeats T, Han H, Jetter R2010 Sep 2420610397