EC number:5.4.99.50

Enzyme

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     5. Isomerases
        5.4 Intramolecular transferases
            5.4.99 Transferring other groups
ID:5.4.99.50
Description:Friedelin synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.4.99.50
BRENDA Enzyme Link: BRENDA 5.4.99.50
KEGG Enzyme Link: KEGG5.4.99.50
BioCyc Enzyme Link: BioCyc 5.4.99.50
ExPASy Enzyme Link: ExPASy5.4.99.50
EC2PDB Enzyme Link: EC2PDB 5.4.99.50
ExplorEnz Enzyme Link: ExplorEnz 5.4.99.50
PRIAM enzyme-specific profiles Link: PRIAM 5.4.99.50
IntEnz Enzyme Link: IntEnz 5.4.99.50
MEDLINE Enzyme Link: MEDLINE 5.4.99.50

EC number:5.4.99.50

MSA:

5.4.99.50;
Phylogenetic Tree:

5.4.99.50;
Uniprot:
M-CSA:
RHEA:31863 (S)-2,3-epoxysqualene = friedelin
RULE(radius=1) [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:8])=[CH;+0:9]-[*:10]-[CH2;+0:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[*:16]-[CH;+0:17]=[C;H0;+0:18](-[*:19])-[*:20]-[*:21]-[CH;+0:22]=[C;H0;+0:23](-[CH3;+0:24])-[*:25]-[*:26]-[CH;+0:27]1-[O;H0;+0:28]-[C;H0;+0:29]-1(-[*:30])-[CH3;+0:31]>>[*:1]-[C;H0;+0:2]12-[CH2;+0:9]-[*:10]-[C;H0;+0:11]3(-[CH3;+0:31])-[CH2;+0:12]-[CH2;+0:14]-[C;H0;+0:15](-[CH3;+0:8])(-[CH3;+0:24])-[*:16]-[CH;+0:17]-3-[C;H0;+0:18]-1(-[*:19])-[*:20]-[*:21]-[C;H0;+0:22]1(-[CH3;+0:13])-[CH;+0:3]-2-[*:4]-[CH2;+0:5]-[C;H0;+0:6]2(-[*:7])-[CH;+0:29](-[*:30])-[C;H0;+0:27](=[O;H0;+0:28])-[*:26]-[*:25]-[CH;+0:23]-2-1
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References

TitleAuthorsDatePubMed ID
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.Wang Z, Yeats T, Han H, Jetter R2010 Sep 2420610397