EC number:5.4.99.60
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.4 Intramolecular transferases |
| 5.4.99 Transferring other groups |
| ID: | 5.4.99.60 |
|---|---|
| Description: | Cobalt-precorrin-8 methylmutase. |
| Cath: | 3.40.50.10230; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.4.99.60 |
| BRENDA Enzyme Link: | BRENDA 5.4.99.60 |
| KEGG Enzyme Link: | KEGG5.4.99.60 |
| BioCyc Enzyme Link: | BioCyc 5.4.99.60 |
| ExPASy Enzyme Link: | ExPASy5.4.99.60 |
| EC2PDB Enzyme Link: | EC2PDB 5.4.99.60 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.4.99.60 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.4.99.60 |
| IntEnz Enzyme Link: | IntEnz 5.4.99.60 |
| MEDLINE Enzyme Link: | MEDLINE 5.4.99.60 |
EC number:5.4.99.60
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:16209 | Co-precorrin-8X = cob(II)yrinate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[*:5]2=[N+;H0:6]3-[C;H0;+0:7]-1(-[CH3;+0:8])-[CH2;+0:9]-[C;H0;+0:10]1=[C;H0;+0:11](-[*:12])-[*:13]-[C;H0;+0:14]4=[N+;H0:15]-1-[Co-2;H0:16]-31-[N+;H0:17]3=[C;H0;+0:18](-[CH;+0:19]-2-[CH3;+0:20])-[C;H0;+0:21](-[*:22])(-[*:23])-[*:24]-[*:25]-3-[*:26]-[N;H0;+0:27]-1-[C;H0;+0:28](-[*:29])=[C;H0;+0:30]-4-[*:31]>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:8])-[C;H0;+0:7]2=[CH;+0:9]-[C;H0;+0:10]3=[N;H0;+0:15]-[C;H0;+0:14](=[C;H0;+0:30](-[*:31])-[C;H0;+0:28](-[*:29])=[N;H0;+0:27]-[*:26]-[*:25]4-[*:24]-[C;H0;+0:21](-[*:22])(-[*:23])-[C;H0;+0:20](=[C;H0;+0:19](-[CH3;+0:18])-[*:5](=[N;H0;+0:6]-2)-[CH;+0:3]-1-[*:4])-[N;H0;+0:17]-4-[Co+;H0:16])-[*:13]-[CH;+0:11]-3-[*:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12). | Moore SJ, Lawrence AD, Biedendieck R, Deery E, Frank S, Howard MJ, Rigby SE, Warren MJ | 2013 Sep 10 | 23922391 |
| The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis. | Xue Y, Wei Z, Li X, Gong W | 2006 Mar | 16427313 |