EC number:5.5.1.15
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.15 |
|---|---|
| Description: | Terpentedienyl-diphosphate synthase. |
| Alternative Name: |
Terpentedienol diphosphate synthase. Clerodadienyl diphosphate synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.15 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.15 |
| KEGG Enzyme Link: | KEGG5.5.1.15 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.15 |
| ExPASy Enzyme Link: | ExPASy5.5.1.15 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.15 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.15 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.15 |
| RHEA:25613 | all-trans-geranylgeranyl diphosphate = terpentedienyl diphosphate |
| RULE(radius=1) | ([*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5]-[*:6]-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[CH3;+0:10].[*:11]=[C;H0;+0:12](-[*:13])-[CH3;+0:14])>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:10])-[CH;+0:3](-[*:4])-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:14])(-[C;H0;+0:12](=[*:11])-[*:13])-[CH;+0:8]-1-[*:9] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A new approach for the investigation of isoprenoid biosynthesis featuring pathway switching, deuterium hyperlabeling, and 1H NMR spectroscopy. The reaction mechanism of a novel streptomyces diterpene cyclase. | Eguchi T, Dekishima Y, Hamano Y, Dairi T, Seto H, Kakinuma K | 2003 Jul 11 | 12839434 |
| Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin. | Hamano Y, Kuzuyama T, Itoh N, Furihata K, Seto H, Dairi T | 2002 Oct 4 | 12138123 |
| Eubacterial diterpene cyclase genes essential for production of the isoprenoid antibiotic terpentecin. | Dairi T, Hamano Y, Kuzuyama T, Itoh N, Furihata K, Seto H | 2001 Oct | 11567009 |