EC number:5.5.1.16
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.16 |
|---|---|
| Description: | Halimadienyl-diphosphate synthase. |
| Alternative Name: |
Tuberculosinol diphosphate synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.16 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.16 |
| KEGG Enzyme Link: | KEGG5.5.1.16 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.16 |
| ExPASy Enzyme Link: | ExPASy5.5.1.16 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.16 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.16 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.16 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.16 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.16 |
| RHEA:25621 | geranylgeranyl diphosphate = tuberculosinyl diphosphate |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5]-[CH2;+0:6]-[CH;+0:7]=[C;H0;+0:8](-[CH3;+0:9])-[*:10]-[*:11]-[CH;+0:12]=[C;H0;+0:13](-[*:14])-[*:15]>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:9])-[CH;+0:3](-[*:4])-[*:5]-[CH;+0:6]=[C;H0;+0:7]2-[CH;+0:8]-1-[*:10]-[*:11]-[CH2;+0:12]-[C;H0;+0:13]-2(-[*:14])-[*:15] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the Rv3377c gene product, a type-B diterpene cyclase, from the Mycobacterium tuberculosis H37 genome. | Nakano C, Hoshino T | 2009 Aug 17 | 19618417 |
| Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton. | Nakano C, Okamura T, Sato T, Dairi T, Hoshino T | 2005 Feb 28 | 15719101 |