EC number:5.5.1.22
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.22 |
|---|---|
| Description: | (-)-bornyl diphosphate synthase. |
| Alternative Name: |
Bornyl pyrophosphate synthase. (-)-bornyl pyrophosphate cyclase. |
| Cath: | 1.10.600.10; 1.50.10.130; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.22 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.22 |
| KEGG Enzyme Link: | KEGG5.5.1.22 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.22 |
| ExPASy Enzyme Link: | ExPASy5.5.1.22 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.22 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.22 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.22 |
| RHEA:32707 | (2E)-geranyl diphosphate = (2R,4S)-bornyl diphosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:8])=[CH;+0:9]-[CH2;+0:10]-[*:11]>>[*:1]-[C;H0;+0:2]1(-[*:3])-[CH;+0:7]2-[*:6]-[*:5]-[C;H0;+0:4]-1(-[CH3;+0:8])-[CH;+0:10](-[*:11])-[CH2;+0:9]-2 |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Monoterpene biosynthesis in the liverwort Conocephalum conicum: demonstration of sabinene synthase and bornyl diphosphate synthase. | Adam KP, Croteau R | 1998 Sep | 9747540 |
| Mechanism of the pyrophosphate migration in the enzymatic cyclization of geranyl and linalyl pyrophosphates to (+)- and (-)-bornyl pyrophosphates. | Croteau RB, Shaskus JJ, Renstrøm B, Felton NM, Cane DE, Saito A, Chang C | 1985 Dec 3 | 4084562 |
| Stereochemistry at C-1 of geranyl pyrophosphate and neryl pyrophosphate in the cyclization to (+)- and (-)-bornyl pyrophosphate. | Croteau R, Felton NM, Wheeler CJ | 1985 May 25 | 3997807 |
| Biosynthesis of monoterpenes: demonstration of a geranyl pyrophosphate:(-)-bornyl pyrophosphate cyclase in soluble enzyme preparations from tansy (Tanacetum vulgare). | Croteau R, Shaskus J | 1985 Feb 1 | 3970524 |
| Biosynthesis of monoterpenes: stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to camphane and isocamphane monoterpenes. | Croteau R, Gershenzon J, Wheeler CJ, Satterwhite DM | 1990 Mar | 2178556 |