EC number:5.5.1.28
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.28 |
|---|---|
| Description: | (-)-kolavenyl diphosphate synthase. |
| Alternative Name: |
CLPP. Clerodienyl diphosphate synthase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.28 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.28 |
| KEGG Enzyme Link: | KEGG5.5.1.28 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.28 |
| ExPASy Enzyme Link: | ExPASy5.5.1.28 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.28 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.28 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.28 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.28 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.28 |
| RHEA:54684 | all-trans-geranylgeranyl diphosphate = (-)-kolavenyl diphosphate |
| RULE(radius=1) | ([*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5]-[*:6]-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[CH3;+0:10].[*:11]=[C;H0;+0:12](-[*:13])-[CH3;+0:14])>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:10])-[CH;+0:3](-[*:4])-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:14])(-[C;H0;+0:12](=[*:11])-[*:13])-[CH;+0:8]-1-[*:9] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A (-)-kolavenyl diphosphate synthase catalyzes the first step of salvinorin A biosynthesis in Salvia divinorum. | Chen X, Berim A, Dayan FE, Gang DR | 2017 Feb 1 | 28204567 |
| The terpene synthase gene family in Tripterygium wilfordii harbors a labdane-type diterpene synthase among the monoterpene synthase TPS-b subfamily. | Hansen NL, Heskes AM, Hamberger B, Olsen CE, Hallström BM, Andersen-Ranberg J, Hamberger B | 2017 Feb | 27801964 |