EC number:5.5.1.32
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.32 |
|---|---|
| Description: | 12-epi-hapalindole U synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.32 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.32 |
| KEGG Enzyme Link: | KEGG5.5.1.32 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.32 |
| ExPASy Enzyme Link: | ExPASy5.5.1.32 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.32 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.32 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.32 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.32 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.32 |
| RHEA:56452 | 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-hapalindole U |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:8])=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11]1(-[CH;+0:12]=[CH;+0:13]-[*:14])-[CH;+0:15]=[N;H0;+0:16]-[c;H0;+0:17]2:[*:18]:[*:19]:[cH;+0:20]:[cH;+0:21]:[c;H0;+0:22]:2-1>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:21])-[CH;+0:3]2-[*:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])(-[CH;+0:8]=[CH2;+0:22])-[CH;+0:13](-[*:14])-[CH;+0:12]-2-[c;H0;+0:11]2:[cH;+0:15]:[nH;+0:16]:[c;H0;+0:17]3:[*:18]:[*:19]:[cH;+0:20]:[c;H0;+0:9]-1:[c;H0;+0:10]:2:3 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade. | Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH | 2015 Dec 16 | 26629885 |