EC number:5.5.1.33
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.5 Intramolecular lyases |
| 5.5.1 Intramolecular lyases (only sub-subclass identified to date) |
| ID: | 5.5.1.33 |
|---|---|
| Description: | 12-epi-fischerindole U synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.5.1.33 |
| BRENDA Enzyme Link: | BRENDA 5.5.1.33 |
| KEGG Enzyme Link: | KEGG5.5.1.33 |
| BioCyc Enzyme Link: | BioCyc 5.5.1.33 |
| ExPASy Enzyme Link: | ExPASy5.5.1.33 |
| EC2PDB Enzyme Link: | EC2PDB 5.5.1.33 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.5.1.33 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.5.1.33 |
| IntEnz Enzyme Link: | IntEnz 5.5.1.33 |
| MEDLINE Enzyme Link: | MEDLINE 5.5.1.33 |
| RHEA:56456 | 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-fischerindole U |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[C;H0;+0:4]1(-[CH2;+0:5]-[CH;+0:6]=[C;H0;+0:7](-[CH3;+0:8])-[*:9]-[*:10]-[CH;+0:11]=[C;H0;+0:12](-[CH3;+0:13])-[CH3;+0:14])-[*:15]:[*:16]-[N;H0;+0:17]=[CH;+0:18]-1>>[*:1]-[CH;+0:2]1-[CH;+0:3]2-[CH;+0:7](-[*:9]-[*:10]-[C;H0;+0:11]-1(-[CH3;+0:14])-[CH;+0:12]=[CH2;+0:13])-[C;H0;+0:6](-[CH3;+0:8])(-[CH3;+0:18])-[c;H0;+0:5]1:[nH;+0:17]:[*:16]:[*:15]:[c;H0;+0:4]:1-2 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids. | Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH | 2017 May | 28288107 |