Enzyme

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     5. Isomerases
        5.5 Intramolecular lyases
            5.5.1 Intramolecular lyases (only sub-subclass identified to date)
ID:5.5.1.8
Description:(+)-bornyl diphosphate synthase.
Alternative Name: Geranyl-diphosphate cyclase.
Bornyl pyrophosphate synthetase.
Bornyl pyrophosphate synthase.
Cath: 1.10.600.10; 1.50.10.130;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.5.1.8
BRENDA Enzyme Link: BRENDA 5.5.1.8
KEGG Enzyme Link: KEGG5.5.1.8
BioCyc Enzyme Link: BioCyc 5.5.1.8
ExPASy Enzyme Link: ExPASy5.5.1.8
EC2PDB Enzyme Link: EC2PDB 5.5.1.8
ExplorEnz Enzyme Link: ExplorEnz 5.5.1.8
PRIAM enzyme-specific profiles Link: PRIAM 5.5.1.8
IntEnz Enzyme Link: IntEnz 5.5.1.8
MEDLINE Enzyme Link: MEDLINE 5.5.1.8
MSA:

5.5.1.8;

Phylogenetic Tree:

5.5.1.8;

Uniprot:
M-CSA:
RHEA:18209 (2E)-geranyl diphosphate = (2S)-bornyl diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:8])=[CH;+0:9]-[CH2;+0:10]-[*:11]>>[*:1]-[C;H0;+0:2]1(-[*:3])-[CH;+0:7]2-[*:6]-[*:5]-[C;H0;+0:4]-1(-[CH3;+0:8])-[CH;+0:10](-[*:11])-[CH2;+0:9]-2
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase.Wise ML, Savage TJ, Katahira E, Croteau R1998 Jun 129614092
Biotransformation of limonene by bacteria, fungi, yeasts, and plants.Duetz WA, Bouwmeester H, van Beilen JB, Witholt B2003 May12743755
Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase.Whittington DA, Wise ML, Urbansky M, Coates RM, Croteau RB, Christianson DW2002 Nov 2612432096