Enzyme

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     6. Ligases
        6.1 Forming carbon-oxygen bonds
            6.1.1 Ligases forming aminoacyl-tRNA and related compounds
ID:6.1.1.10
Description:Methionine--tRNA ligase.
Alternative Name: MetRS.
Methionyl-tRNA synthetase.
Methionyl-transfer RNA synthetase.
Methionyl-transfer ribonucleic acid synthetase.
Methionyl-transfer ribonucleate synthetase.
Methionine translase.
Prosite: PDOC00161;
PDB:
PDBScop
Cath: 1.10.220.140; 1.10.287.10; 1.10.730.10; 1.20.1050.10; 1.20.1050.110; 3.40.50.620; 2.170.220.10; 2.20.28.20; 2.40.50.140; 3.40.30.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.1.1.10
BRENDA Enzyme Link: BRENDA 6.1.1.10
KEGG Enzyme Link: KEGG6.1.1.10
BioCyc Enzyme Link: BioCyc 6.1.1.10
ExPASy Enzyme Link: ExPASy6.1.1.10
EC2PDB Enzyme Link: EC2PDB 6.1.1.10
ExplorEnz Enzyme Link: ExplorEnz 6.1.1.10
PRIAM enzyme-specific profiles Link: PRIAM 6.1.1.10
IntEnz Enzyme Link: IntEnz 6.1.1.10
MEDLINE Enzyme Link: MEDLINE 6.1.1.10
MSA:

6.1.1.10;

Phylogenetic Tree:

6.1.1.10;

Uniprot:
M-CSA:
RHEA:13481 ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction