EC number:6.1.1.11
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.1 Forming carbon-oxygen bonds |
| 6.1.1 Ligases forming aminoacyl-tRNA and related compounds |
| ID: | 6.1.1.11 | ||
|---|---|---|---|
| Description: | Serine--tRNA ligase. | ||
| Alternative Name: |
Seryl-tRNA synthetase. Seryl-transfer RNA synthetase. Seryl-transfer ribonucleic acid synthetase. Seryl-transfer ribonucleate synthetase. SerRS. Serine translase. | ||
| Prosite: | PDOC00363; | ||
| PDB: |
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| Cath: | 1.10.287.40; 3.30.70.1920; 3.30.930.10; 1.20.920.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.1.1.11 |
| BRENDA Enzyme Link: | BRENDA 6.1.1.11 |
| KEGG Enzyme Link: | KEGG6.1.1.11 |
| BioCyc Enzyme Link: | BioCyc 6.1.1.11 |
| ExPASy Enzyme Link: | ExPASy6.1.1.11 |
| EC2PDB Enzyme Link: | EC2PDB 6.1.1.11 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.1.1.11 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.1.1.11 |
| IntEnz Enzyme Link: | IntEnz 6.1.1.11 |
| MEDLINE Enzyme Link: | MEDLINE 6.1.1.11 |
| RHEA:42580 | ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Selenocysteine tRNA and serine tRNA are aminoacylated by the same synthetase, but may manifest different identities with respect to the long extra arm. | Ohama T, Yang DC, Hatfield DL | 1994 Dec | 7986071 |
| RHEA:12292 | ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |