EC number:6.1.1.14
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.1 Forming carbon-oxygen bonds |
| 6.1.1 Ligases forming aminoacyl-tRNA and related compounds |
| ID: | 6.1.1.14 | ||
|---|---|---|---|
| Description: | Glycine--tRNA ligase. | ||
| Alternative Name: |
Glycyl-tRNA synthetase. Glycyl translase. | ||
| Prosite: | PDOC00363; | ||
| PDB: |
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| Cath: | 1.10.30.30; 1.20.1430.20; 3.30.930.10; 3.40.50.80; 3.40.50.800; 1.20.58.180; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.1.1.14 |
| BRENDA Enzyme Link: | BRENDA 6.1.1.14 |
| KEGG Enzyme Link: | KEGG6.1.1.14 |
| BioCyc Enzyme Link: | BioCyc 6.1.1.14 |
| ExPASy Enzyme Link: | ExPASy6.1.1.14 |
| EC2PDB Enzyme Link: | EC2PDB 6.1.1.14 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.1.1.14 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.1.1.14 |
| IntEnz Enzyme Link: | IntEnz 6.1.1.14 |
| MEDLINE Enzyme Link: | MEDLINE 6.1.1.14 |
| RHEA:16013 | ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of the peptidoglycan of bacterial cell walls. IX. Purification and properties of glycyl transfer ribonucleic acid synthetase from Staphylococcus aureus. | Niyomporn B, Dahl JL, Strominger JL | 1968 Feb 25 | 4295604 |
| Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. | Cader MZ, Ren J, James PA, Bird LE, Talbot K, Stammers DK | 2007 Jun 26 | 17544401 |
| Glycyl-RNA synthetase of rat liver: partial purification and effects of some metal ions on its activity. | FRASER MJ | 1963 May | 13959340 |
| Overlapping destinations for two dual targeted glycyl-tRNA synthetases in Arabidopsis thaliana and Phaseolus vulgaris. | Duchêne AM, Peeters N, Dietrich A, Cosset A, Small ID, Wintz H | 2001 May 4 | 11278923 |