EC number:6.1.1.17

Enzyme

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     6. Ligases
        6.1 Forming carbon-oxygen bonds
            6.1.1 Ligases forming aminoacyl-tRNA and related compounds
ID:6.1.1.17
Description:Glutamate--tRNA ligase.
Alternative Name: Glutamyl-tRNA synthetase.
Glutamic acid translase.
Prosite: PDOC00161;
PDB:
PDBScop
Cath: 1.10.10.350; 1.10.1160.10; 1.10.20.60; 1.10.287.10; 1.10.8.70; 1.20.1050.10; 1.20.1050.130; 3.30.110.30; 3.30.930.10; 3.40.50.620;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.1.1.17
BRENDA Enzyme Link: BRENDA 6.1.1.17
KEGG Enzyme Link: KEGG6.1.1.17
BioCyc Enzyme Link: BioCyc 6.1.1.17
ExPASy Enzyme Link: ExPASy6.1.1.17
EC2PDB Enzyme Link: EC2PDB 6.1.1.17
ExplorEnz Enzyme Link: ExplorEnz 6.1.1.17
PRIAM enzyme-specific profiles Link: PRIAM 6.1.1.17
IntEnz Enzyme Link: IntEnz 6.1.1.17
MEDLINE Enzyme Link: MEDLINE 6.1.1.17

EC number:6.1.1.17

MSA:

6.1.1.17;
Phylogenetic Tree:

6.1.1.17;
Uniprot:
M-CSA:
RHEA:23540 ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[O;H0;+0:6]-[P;H0;+0:7](-[*:8])(=[*:9])-[*:10].[*:11]-[OH;+0:12]>>[*:11]-[O;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3].[*:5]-[OH;+0:6].[*:8]-[P;H0;+0:7](=[*:9])(-[*:10])-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
GLUTAMYL AND GLUTAMINYL RIBONUCLEIC ACID SYNTHETASES OF ESCHERICHIA COLI W. SEPARATION, PROPERTIES, AND STIMULATION OF ADENOSINE TRIPHOSPHATE-PYROPHOSPHATE EXCHANGE BY ACCEPTOR RIBONUCLEIC ACID.RAVEL JM, WANG SF, HEINEMEYER C, SHIVE W1965 Jan14253448
The glutamyl-tRNA synthetase of Escherichia coli contains one atom of zinc essential for its native conformation and its catalytic activity.Liu J, Lin SX, Blochet JE, Pézolet M, Lapointe J1993 Oct 268218204
Arc1p organizes the yeast aminoacyl-tRNA synthetase complex and stabilizes its interaction with the cognate tRNAs.Deinert K, Fasiolo F, Hurt EC, Simos G2001 Feb 2311069915