EC number:6.1.1.18
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.1 Forming carbon-oxygen bonds |
| 6.1.1 Ligases forming aminoacyl-tRNA and related compounds |
| ID: | 6.1.1.18 | ||
|---|---|---|---|
| Description: | Glutamine--tRNA ligase. | ||
| Alternative Name: |
Glutaminyl-tRNA synthetase. Glutamine translase. | ||
| Prosite: | PDOC00161; | ||
| PDB: |
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| Cath: | 1.10.10.2420; 1.10.1160.10; 1.10.287.2340; 1.10.8.1290; 3.40.50.620; 3.90.1300.10; 3.90.800.10; 2.40.240.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.1.1.18 |
| BRENDA Enzyme Link: | BRENDA 6.1.1.18 |
| KEGG Enzyme Link: | KEGG6.1.1.18 |
| BioCyc Enzyme Link: | BioCyc 6.1.1.18 |
| ExPASy Enzyme Link: | ExPASy6.1.1.18 |
| EC2PDB Enzyme Link: | EC2PDB 6.1.1.18 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.1.1.18 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.1.1.18 |
| IntEnz Enzyme Link: | IntEnz 6.1.1.18 |
| MEDLINE Enzyme Link: | MEDLINE 6.1.1.18 |
| RHEA:20121 | ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| How glutaminyl-tRNA synthetase selects glutamine. | Rath VL, Silvian LF, Beijer B, Sproat BS, Steitz TA | 1998 Apr 15 | 9562563 |
| The structure of yeast glutaminyl-tRNA synthetase and modeling of its interaction with tRNA. | Grant TD, Luft JR, Wolfley JR, Snell ME, Tsuruta H, Corretore S, Quartley E, Phizicky EM, Grayhack EJ, Snell EH | 2013 Jul 24 | 23583912 |
| GLUTAMYL AND GLUTAMINYL RIBONUCLEIC ACID SYNTHETASES OF ESCHERICHIA COLI W. SEPARATION, PROPERTIES, AND STIMULATION OF ADENOSINE TRIPHOSPHATE-PYROPHOSPHATE EXCHANGE BY ACCEPTOR RIBONUCLEIC ACID. | RAVEL JM, WANG SF, HEINEMEYER C, SHIVE W | 1965 Jan | 14253448 |