Enzyme

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     6. Ligases
        6.1 Forming carbon-oxygen bonds
            6.1.1 Ligases forming aminoacyl-tRNA and related compounds
ID:6.1.1.2
Description:Tryptophan--tRNA ligase.
Alternative Name: Tryptophanyl-tRNA synthetase.
Tryptophanyl-tRNA synthase.
Tryptophanyl-transfer RNA synthetase.
Tryptophanyl-transfer ribonucleic synthetase.
Tryptophanyl-transfer ribonucleic acid synthetase.
Tryptophanyl-transfer ribonucleate synthetase.
Tryptophanyl ribonucleic synthetase.
Tryptophan translase.
TrpRS.
L-tryptophan-tRNA(Trp) ligase (AMP-forming).
Prosite: PDOC00161;
PDB:
PDBScop
Cath: 1.10.240.10; 1.10.287.10; 3.40.50.620;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.1.1.2
BRENDA Enzyme Link: BRENDA 6.1.1.2
KEGG Enzyme Link: KEGG6.1.1.2
BioCyc Enzyme Link: BioCyc 6.1.1.2
ExPASy Enzyme Link: ExPASy6.1.1.2
EC2PDB Enzyme Link: EC2PDB 6.1.1.2
ExplorEnz Enzyme Link: ExplorEnz 6.1.1.2
PRIAM enzyme-specific profiles Link: PRIAM 6.1.1.2
IntEnz Enzyme Link: IntEnz 6.1.1.2
MEDLINE Enzyme Link: MEDLINE 6.1.1.2
MSA:

6.1.1.2;

Phylogenetic Tree:

6.1.1.2;

Uniprot:
M-CSA:
RHEA:24080 ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12]
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