EC number:6.1.1.23
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.1 Forming carbon-oxygen bonds |
| 6.1.1 Ligases forming aminoacyl-tRNA and related compounds |
| ID: | 6.1.1.23 |
|---|---|
| Description: | Aspartate--tRNA(Asn) ligase. |
| Alternative Name: |
Nondiscriminating aspartyl-tRNA synthetase. |
| Cath: | 3.30.1360.30; 3.30.930.10; 2.40.50.140; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.1.1.23 |
| BRENDA Enzyme Link: | BRENDA 6.1.1.23 |
| KEGG Enzyme Link: | KEGG6.1.1.23 |
| BioCyc Enzyme Link: | BioCyc 6.1.1.23 |
| ExPASy Enzyme Link: | ExPASy6.1.1.23 |
| EC2PDB Enzyme Link: | EC2PDB 6.1.1.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.1.1.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.1.1.23 |
| IntEnz Enzyme Link: | IntEnz 6.1.1.23 |
| MEDLINE Enzyme Link: | MEDLINE 6.1.1.23 |
| RHEA:18349 | ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[O;H0;+0:6]-[P;H0;+0:7](-[*:8])(=[*:9])-[*:10].[*:11]-[OH;+0:12]>>[*:11]-[O;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3].[*:5]-[OH;+0:6].[*:8]-[P;H0;+0:7](=[*:9])(-[*:10])-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Thermus thermophilus: a link in evolution of the tRNA-dependent amino acid amidation pathways. | Becker HD, Kern D | 1998 Oct 27 | 9789000 |
| Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation. | Schmitt E, Moulinier L, Fujiwara S, Imanaka T, Thierry JC, Moras D | 1998 Sep 1 | 9724658 |
| Aminoacyl-tRNA synthesis. | Ibba M, Soll D | 2000 | 10966471 |