EC number:6.1.1.4

Enzyme

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EC Tree
     6. Ligases
        6.1 Forming carbon-oxygen bonds
            6.1.1 Ligases forming aminoacyl-tRNA and related compounds
ID:6.1.1.4
Description:Leucine--tRNA ligase.
Alternative Name: Leucyl-tRNA synthetase.
Leucine translase.
Prosite: PDOC00161;
PDB:
PDBScop
Cath: 1.10.10.720; 1.10.730.10; 3.30.2320.20; 3.40.50.620; 3.90.740.10; 2.30.210.10; 3.10.20.590; 3.10.330.110;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.1.1.4
BRENDA Enzyme Link: BRENDA 6.1.1.4
KEGG Enzyme Link: KEGG6.1.1.4
BioCyc Enzyme Link: BioCyc 6.1.1.4
ExPASy Enzyme Link: ExPASy6.1.1.4
EC2PDB Enzyme Link: EC2PDB 6.1.1.4
ExplorEnz Enzyme Link: ExplorEnz 6.1.1.4
PRIAM enzyme-specific profiles Link: PRIAM 6.1.1.4
IntEnz Enzyme Link: IntEnz 6.1.1.4
MEDLINE Enzyme Link: MEDLINE 6.1.1.4

EC number:6.1.1.4

MSA:

6.1.1.4;
Phylogenetic Tree:

6.1.1.4;
Uniprot:
M-CSA:
RHEA:11688 ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11].[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction