EC number:6.2.1.10

Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.10
Description:Acid--CoA ligase (GDP-forming).
Alternative Name: Acyl-CoA synthetase (GDP-forming).

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.10
BRENDA Enzyme Link: BRENDA 6.2.1.10
KEGG Enzyme Link: KEGG6.2.1.10
BioCyc Enzyme Link: BioCyc 6.2.1.10
ExPASy Enzyme Link: ExPASy6.2.1.10
EC2PDB Enzyme Link: EC2PDB 6.2.1.10
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.10
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.10
IntEnz Enzyme Link: IntEnz 6.2.1.10
MEDLINE Enzyme Link: MEDLINE 6.2.1.10

EC number:6.2.1.10

MSA:

6.2.1.10;
Phylogenetic Tree:

6.2.1.10;
Uniprot:
M-CSA:
RHEA:10968 a carboxylate + CoA + GTP = an acyl-CoA + GDP + phosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[O;H0;+0:6]-[P;H0;+0:7](=[*:8])(-[*:9])-[*:10].[*:11]-[SH;+0:12]>>[*:5]-[OH;+0:6].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3].[*:8]=[P;H0;+0:7](-[*:9])(-[*:10])-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
ACTIVATION OF FATTY ACIDS BY A GUANOSINE TRIPHOSPHATE-SPECIFIC THIOKINASE FROM LIVER MITOCHONDRIA.ROSSI CR, GIBSON DM1964 Jun14213337