EC number:6.2.1.11

Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.11
Description:Biotin--CoA ligase.
Alternative Name: Biotinyl-CoA synthetase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.11
BRENDA Enzyme Link: BRENDA 6.2.1.11
KEGG Enzyme Link: KEGG6.2.1.11
BioCyc Enzyme Link: BioCyc 6.2.1.11
ExPASy Enzyme Link: ExPASy6.2.1.11
EC2PDB Enzyme Link: EC2PDB 6.2.1.11
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.11
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.11
IntEnz Enzyme Link: IntEnz 6.2.1.11
MEDLINE Enzyme Link: MEDLINE 6.2.1.11

EC number:6.2.1.11

MSA:

6.2.1.11;
Phylogenetic Tree:

6.2.1.11;
Uniprot:
M-CSA:
RHEA:19681 ATP + biotin + CoA = AMP + biotinyl-CoA + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[O;H0;+0:9]-[*:10].[*:11]-[SH;+0:12]>>[*:10]-[OH;+0:9].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[OH;+0:4].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
ENZYMATIC ACTIVATION OF BIOTIN. BIOTINYL ADENYLATE FORMATION.CHRISTNER JE, SCHLESINGER MJ, COON MJ1964 Nov14257635