Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.16
Description:Acetoacetate--CoA ligase.
Alternative Name: Acetoacetyl-CoA synthetase.
Prosite: PDOC00427;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.16
BRENDA Enzyme Link: BRENDA 6.2.1.16
KEGG Enzyme Link: KEGG6.2.1.16
BioCyc Enzyme Link: BioCyc 6.2.1.16
ExPASy Enzyme Link: ExPASy6.2.1.16
EC2PDB Enzyme Link: EC2PDB 6.2.1.16
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.16
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.16
IntEnz Enzyme Link: IntEnz 6.2.1.16
MEDLINE Enzyme Link: MEDLINE 6.2.1.16
MSA:

6.2.1.16;

Phylogenetic Tree:

6.2.1.16;

Uniprot:
M-CSA:
RHEA:16117 acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate
RULE(radius=1) [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction