EC number:6.2.1.17

Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.17
Description:Propionate--CoA ligase.
Alternative Name: Propionyl-CoA synthetase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.17
BRENDA Enzyme Link: BRENDA 6.2.1.17
KEGG Enzyme Link: KEGG6.2.1.17
BioCyc Enzyme Link: BioCyc 6.2.1.17
ExPASy Enzyme Link: ExPASy6.2.1.17
EC2PDB Enzyme Link: EC2PDB 6.2.1.17
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.17
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.17
IntEnz Enzyme Link: IntEnz 6.2.1.17
MEDLINE Enzyme Link: MEDLINE 6.2.1.17

EC number:6.2.1.17

MSA:

6.2.1.17;
Phylogenetic Tree:

6.2.1.17;
Uniprot:
M-CSA:
RHEA:20373 ATP + CoA + propanoate = AMP + diphosphate + propanoyl-CoA
RULE(radius=1) [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular cloning of rat acss3 and characterization of mammalian propionyl-CoA synthetase in the liver mitochondrial matrix.Yoshimura Y, Araki A, Maruta H, Takahashi Y, Yamashita H2017 Mar 128003429
Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.Fujino T, Takei YA, Sone H, Ioka RX, Kamataki A, Magoori K, Takahashi S, Sakai J, Yamamoto TT2001 Sep 2111470804