EC number:6.2.1.18
| ID: | 6.2.1.18 |
|---|---|
| Description: | Citrate--CoA ligase. |
| Cath: | 3.30.1490.20; 3.30.470.110; 3.30.470.20; 3.40.50.720; 3.40.50.261; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.2.1.18 |
| BRENDA Enzyme Link: | BRENDA 6.2.1.18 |
| KEGG Enzyme Link: | KEGG6.2.1.18 |
| BioCyc Enzyme Link: | BioCyc 6.2.1.18 |
| ExPASy Enzyme Link: | ExPASy6.2.1.18 |
| EC2PDB Enzyme Link: | EC2PDB 6.2.1.18 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.2.1.18 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.2.1.18 |
| IntEnz Enzyme Link: | IntEnz 6.2.1.18 |
| MEDLINE Enzyme Link: | MEDLINE 6.2.1.18 |
| RHEA:21472 | ATP + citrate + CoA = (3S)-citryl-CoA + ADP + phosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[SH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:5]-[S;H0;+0:6]-[C;H0;+0:2](-[*:1])=[*:3].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase. | Lill U, Schreil A, Eggerer H | 1982 Jul | 6749502 |
| A novel enzyme, citryl-CoA synthetase, catalysing the first step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6. | Aoshima M, Ishii M, Igarashi Y | 2004 May | 15101981 |