EC number:6.2.1.2

Enzyme

Download
EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.2
Description:Medium-chain acyl-CoA ligase.
Alternative Name: Fatty acid thiokinase (medium chain).
Butyryl-CoA synthetase.
Acyl-activating enzyme.
Cath: 3.30.300.30; 3.40.50.12780;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.2
BRENDA Enzyme Link: BRENDA 6.2.1.2
KEGG Enzyme Link: KEGG6.2.1.2
BioCyc Enzyme Link: BioCyc 6.2.1.2
ExPASy Enzyme Link: ExPASy6.2.1.2
EC2PDB Enzyme Link: EC2PDB 6.2.1.2
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.2
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.2
IntEnz Enzyme Link: IntEnz 6.2.1.2
MEDLINE Enzyme Link: MEDLINE 6.2.1.2

EC number:6.2.1.2

MSA:

6.2.1.2;
Phylogenetic Tree:

6.2.1.2;
Uniprot:
M-CSA:
RHEA:48340 a medium chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate
RULE(radius=1) [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Genetics of alkane oxidation by Pseudomonas oleovorans.van Beilen JB, Wubbolts MG, Witholt B1994 Dec7532480