EC number:6.2.1.23

Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.23
Description:Dicarboxylate--CoA ligase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.23
BRENDA Enzyme Link: BRENDA 6.2.1.23
KEGG Enzyme Link: KEGG6.2.1.23
BioCyc Enzyme Link: BioCyc 6.2.1.23
ExPASy Enzyme Link: ExPASy6.2.1.23
EC2PDB Enzyme Link: EC2PDB 6.2.1.23
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.23
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.23
IntEnz Enzyme Link: IntEnz 6.2.1.23
MEDLINE Enzyme Link: MEDLINE 6.2.1.23

EC number:6.2.1.23

MSA:

6.2.1.23;
Phylogenetic Tree:

6.2.1.23;
Uniprot:
M-CSA:
RHEA:14289 a dicarboxylate + ATP + CoA = AMP + diphosphate + omega-dicarboxyl-CoA
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[O;H0;+0:9]-[*:10].[*:11]-[SH;+0:12]>>[*:10]-[OH;+0:9].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[OH;+0:4].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The microsomal dicarboxylyl-CoA synthetase.Vamecq J, de Hoffmann E, Van Hoof F1985 Sep 154062873