EC number:6.2.1.3
| ID: | 6.2.1.3 | ||
|---|---|---|---|
| Description: | Long-chain-fatty-acid--CoA ligase. | ||
| Alternative Name: |
Lignoceroyl-CoA synthase. Fatty acid thiokinase (long chain). Acyl-CoA synthetase. Acyl-activating enzyme. | ||
| Prosite: | PDOC00427; | ||
| PDB: |
|
||
| Cath: | 3.30.300.30; 3.30.300.310; 3.40.50.12780; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.2.1.3 |
| BRENDA Enzyme Link: | BRENDA 6.2.1.3 |
| KEGG Enzyme Link: | KEGG6.2.1.3 |
| BioCyc Enzyme Link: | BioCyc 6.2.1.3 |
| ExPASy Enzyme Link: | ExPASy6.2.1.3 |
| EC2PDB Enzyme Link: | EC2PDB 6.2.1.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.2.1.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.2.1.3 |
| IntEnz Enzyme Link: | IntEnz 6.2.1.3 |
| MEDLINE Enzyme Link: | MEDLINE 6.2.1.3 |
| RHEA:15421 | a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[O;H0;+0:9]-[*:10].[*:11]-[SH;+0:12]>>[*:10]-[OH;+0:9].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[OH;+0:4].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of long-chain acyl-coenzyme-A synthetase from rat liver. | Tanaka T, Hosaka K, Hoshimaru M, Numa S | 1979 Jul | 467438 |
| Lignoceroyl-coenzyme A synthetase from developing rat brain: partial purification, characterization and comparison with palmitoyl-coenzyme A synthetase activity and liver enzyme. | Nagamatsu K, Soeda S, Mori M, Kishimoto Y | 1985 Aug 22 | 3161545 |
| Identical subcellular distribution of palmitoyl-CoA and arachidonoyl-CoA synthetase activities in human blood platelets. | Bakken AM, Farstad M | 1989 Jul 1 | 2528345 |
| Acyl-coenzyme-A synthetase I from Candida lipolytica. Purification, properties and immunochemical studies. | Hosaka K, Mishina M, Tanaka T, Kamiryo T, Numa S | 1979 Jan 2 | 108099 |