EC number:6.2.1.40
| ID: | 6.2.1.40 |
|---|---|
| Description: | 4-hydroxybutyrate--CoA ligase (AMP-forming). |
| Alternative Name: |
4-hydroxybutyrate-CoA synthetase. 4-hydroxybutyrate--CoA ligase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.2.1.40 |
| BRENDA Enzyme Link: | BRENDA 6.2.1.40 |
| KEGG Enzyme Link: | KEGG6.2.1.40 |
| BioCyc Enzyme Link: | BioCyc 6.2.1.40 |
| ExPASy Enzyme Link: | ExPASy6.2.1.40 |
| EC2PDB Enzyme Link: | EC2PDB 6.2.1.40 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.2.1.40 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.2.1.40 |
| IntEnz Enzyme Link: | IntEnz 6.2.1.40 |
| MEDLINE Enzyme Link: | MEDLINE 6.2.1.40 |
| RHEA:23128 | 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + diphosphate |
| RULE(radius=1) | [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea. | Hawkins AS, Han Y, Bennett RK, Adams MW, Kelly RM | 2013 Feb 8 | 23258541 |
| Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota. | Ramos-Vera WH, Weiss M, Strittmatter E, Kockelkorn D, Fuchs G | 2011 Mar | 21169482 |