EC number:6.2.1.44
| ID: | 6.2.1.44 |
|---|---|
| Description: | 3-(methylthio)propionyl--CoA ligase. |
| Alternative Name: |
MMPA-CoA ligase. Methylmercaptopropionate-coenzyme A ligase. 3-methylmercaptopropionyl-CoA ligase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.2.1.44 |
| BRENDA Enzyme Link: | BRENDA 6.2.1.44 |
| KEGG Enzyme Link: | KEGG6.2.1.44 |
| BioCyc Enzyme Link: | BioCyc 6.2.1.44 |
| ExPASy Enzyme Link: | ExPASy6.2.1.44 |
| EC2PDB Enzyme Link: | EC2PDB 6.2.1.44 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.2.1.44 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.2.1.44 |
| IntEnz Enzyme Link: | IntEnz 6.2.1.44 |
| MEDLINE Enzyme Link: | MEDLINE 6.2.1.44 |
| RHEA:43052 | 3-(methylsulfanyl)propanoate + ATP + CoA = 3-(methylsulfanyl)propanoyl-CoA + AMP + diphosphate |
| RULE(radius=1) | [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Regulatory and functional diversity of methylmercaptopropionate coenzyme A ligases from the dimethylsulfoniopropionate demethylation pathway in Ruegeria pomeroyi DSS-3 and other proteobacteria. | Bullock HA, Reisch CR, Burns AS, Moran MA, Whitman WB | 2014 Mar | 24443527 |
| Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria. | Reisch CR, Stoudemayer MJ, Varaljay VA, Amster IJ, Moran MA, Whitman WB | 2011 May 12 | 21562561 |