EC number:6.2.1.46

Enzyme

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EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.46
Description:L-allo-isoleucine--holo-[CmaA peptidyl-carrier protein] ligase.
Alternative Name: L-allo-isoleucine:holo-[CmaA peptidyl-carrier protein] ligase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.46
BRENDA Enzyme Link: BRENDA 6.2.1.46
KEGG Enzyme Link: KEGG6.2.1.46
BioCyc Enzyme Link: BioCyc 6.2.1.46
ExPASy Enzyme Link: ExPASy6.2.1.46
EC2PDB Enzyme Link: EC2PDB 6.2.1.46
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.46
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.46
IntEnz Enzyme Link: IntEnz 6.2.1.46
MEDLINE Enzyme Link: MEDLINE 6.2.1.46

EC number:6.2.1.46

MSA:

6.2.1.46;
Phylogenetic Tree:

6.2.1.46;
Uniprot:
M-CSA:
RHEA:45624 ATP + holo-[CmaA peptidyl-carrier protein] + L-alloisoleucine = AMP + diphosphate + L-alloisoleucyl-[CmaA peptidyl-carrier protein]
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:12].[*:7]-[S;H0;+0:8]-[C;H0;+0:10](=[*:9])-[*:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine.Couch R, O'Connor SE, Seidle H, Walsh CT, Parry R2004 Jan14679222